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Many organs form by branching of epithelia through the formation of clefts and buds.
Many organs form by branching of epithelia through the formation of clefts and buds during embryonic development.
The pathogenesis of LDD involves the degradation of the normal disc matrix into a disorganized fibrous and less cartilaginous disc, progressing to the formation of clefts and fissures and ultimately compromising the disc integrity [ 5].
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Muscimol injection suppressed the formation of cleft palate in about 20% of the ViaatlacZ homozygous mutant embryos and in about half of the Gad1 homozygous mutant embryos (Table 2).
Inclusion of collectrin antisense ODN was associated with formation of cleft-like structure (arrows) in the ureteric bud branches in a dose-dependent manner (Figures 7a-C and -D).
The failure of palatal shelf elevation resulted in the formation of cleft palate.
It has been well documented that disruption of structural and regulatory genes involved in any stage of palatogenesis, which occurs between E11.5 and E16.5 in mice, contributes to the formation of cleft palate [ 34].
Kcnj13 was identified as one of 8 genes whose mis-expression correlates with formation of cleft palate in TGF3beta knockouts, though the precise role of the channel remains to be described (Ozturk et al, 2013).
Hyperplastic epidermidis was characterized by the formation of acantholytic clefts and the presence of displastic cells and mitotic activity.
McKiernan et al. [ 7] had reported that SuLR could demonstrate the dynamic mobility of the vertebral body and formation of intravertebral clefts (IVCs) in nonunion of VCFs.
Addition of HNF-1α antisense ODN into the metanephric organ culture media also resulted in the formation of multiple cleft-like cysts (Figures 7a-E-F), while the number or size of the cyst formation were relatively more in the metanephroi with the treatment of HNF1-β antisense ODN (Figures 7a-G and H).
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CEO of Professional Science Editing for Scientists @ prosciediting.com