Sentence examples for formation of aggregation from inspiring English sources

In contrast, higher temperature heating can induce important changes in loess properties due to the formation of aggregation as a result of changes in structure and composition.

After binding of the scFv to Aβ monomers, the formation of aggregation seeds and potentially toxic higher order species, such as oligomers and fibrils, was inhibited [47].

Aggregation might be inhibited or disturbed when the concentration of an interfering agent is sufficient to modulate the formation of aggregation seeds as it is the case for human serum albumin (HSA) [59].

It could be hypothesized that the hydrophilic surface of MCHODN NPs suppresses the formation of aggregation followed by nonspecific adhesion to the cell surface.

By keeping the effective intracellular concentration of an aggregation prone protein generally below its critical concentration, the cell may prevent unwanted formation of aggregation nuclei of critical size and polymerization.

Given the fact that these three parameters have no effect on the formation of aggregations, it is consistent with our previous analysis that aggregation rate and size are the main factors determining the peak position.

Thus, DNA binding provides an avenue both to acquire a local and high concentration enough to facilitate the formation of aggregation-prone protein conformations and to enable the protein aggregation.

This reversible interaction reduces the formation of aggregation-prone late unfolding intermediates [ 8, 9].

However, even for proteins that fold successfully to their native structure and hence escape the cellular quality control machinery, random conformational fluctuations of the native protein can lead to the transient formation of aggregation-prone intermediate states (see above).

Next to being utilised as conformational switches [196], proline residues may also provide a protective mechanism, by introducing high energy barriers on the folding energy landscape that disfavour the unfolding of the native state and the formation of aggregation-prone partially folded species [83].

We believe that the buried stress associated with the PPII deformation provides the impetus to rapidly disassociate the filaments into micellar assemblies and monomers at pH ∼ 7. It has been shown by Meredith and co-workers that addition of a polyproline segment to the C-terminus of a polyglutamine sequence inhibits the formation of aggregation-prone β-sheets.