Sentence examples for formation of a platform from inspiring English sources

These enzymes are critical in controlling the formation of a platform structure, sialyl Lewis x (sLex), on circulating cells that plays a central role in the recognition and recruitment by selectin counter receptors on endothelial cells that line blood vessels of tissues throughout the body.

tBid is in turn the driving force destabilizing the vesicles, presumably through increased membrane curvature as described by Epand et al. Indeed, our approach, based on flow cytometry with the newly developed biomimetic model of mitochondrial contact sites, strongly supports the hypothesis of the formation of a platform composed of caspase-8 and Bid-FL bound to CL.

In a continued effort to engage with the state in a technical capacity, SAHAYOG then began strategically working with UNICEF to promote the formation of a platform of development partners and NGOs working within Uttar Pradesh on maternal, newborn, child health and nutrition (MNCHN), in an attempt to re-activate the Technical Support group with the government.

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The electrochemical deposition of chitosan onto carbon felt followed by further modification with alginate led to the formation of a biocompatible platform for the prolific growth of microorganisms on the anode (Chit Alg/carbon felt anode).

Apaf-1 performs its cellular function by the formation of a heptameric platform, dubbed apoptosome, ultimately triggering the controlled demise of the affected cell.

Concomitant conformational changes unlock the NACHT domain leading to oligomerization and the formation of a signaling platform, which is capable of eliciting specific immune responses by the recruitment of specific adaptor molecules as well as effector molecules like inflammatory pro-caspases and kinases [14].

The conformational organization may be advantageous in the formation of a molecular platform that assembles multiple proteins.

cGAMP is a high affinity ligand for STING and induces a change in its conformation allowing for the formation of a signalling platform that activates IRF3 via its kinase TBK1 58– 61 (Fig. 2).

Thus, in ECs, RIN2 appears to act as a docking adaptor protein that, on early endosomes, initiates the formation of a synergistic platform hinged on R-Ras and Rab5 GTPases that then sparks off a pro-adhesive signal.

Caspase-1 is a member of the family of inflammatory caspases that include caspase-4, caspase-5, caspase-11 and caspase-12; in the context of IL-1β processing, caspase-1 accounts for the major activity that requires the formation of a molecular platform known as the inflammasome (reviewed in [ 24]).