Findings of our study may have implications on further research on the pathophysiology of osteoporosis, urinary stone formation and hypertension associated with excessive salt intake.
Inhibition of ET production which resulted in inhibition of ET induced vasoconstriction and mitosis can also inhibit formation of hypertension and cardiac hypertrophy.
The etiology of pain in pancreatitis is multifactorial and may originate from acinar necrosis, pseudocyst formation, ductal hypertension, bile duct obstruction, and/or neurogenic inflammation; as such, the presentations of pain vary among patients.
Pulmonary vascular injury by toxins can induce neointimal formation, pulmonary arterial hypertension (PAH), right ventricular failure, and death.
Simvastatin attenuates monocrotaline-induced pulmonary vascular remodeling with neointimal formation, pulmonary arterial hypertension, and right ventricular hypertrophy in rats.
Edema formation and pulmonary hypertension (PHTN) result from derangements in endothelial, smooth muscle (SM), and/or adventitial fibroblast cell phenotype.
The antiproliferative immunosuppressant, triptolide, attenuates neointimal formation and pulmonary hypertension in this disease model (Faul JL, Nishimura T, Berry GJ, Benson GV, Pearl RG, and Kao PN. Am J Respir Crit Care Med 162: 2000-2000, 2000).
The clinical manifestations include pulmonary hypertension, formation of extravascular lung water (EVLW), and deterioration of pulmonary gas exchange.
In case of prolonged headache not improved by analgesics, it is advisable to perform ophthalmoscopy and brain MRI to exclude volume formations and intracranial hypertension.
The most common complications of IRU in our cohort were cataract formation, glaucoma and ocular hypertension.
There are indications that stone formation can lead to hypertension, diabetes, chronic disease, and myocardial infarct.
