We cultured HUVEC cells from a single batch to various passages (P6, P14, P22) and tested them for cord formation competence.
The vicKR TCS plays a major role in the biofilm formation, competence development, oxidative stress tolerance, acid tolerance, autolysin production, glucan and fructan metabolism of S. mutans[ 27, 72– 72].
Biofilm formation and competence pathways are linked in some bacteria through quorum sensing, so we hypothesize that MUC5B may inhibit natural transformation of S. mutans.
At relatively high bacterial population densities, these autoinducers can locally accumulate and trigger population-wide changes in gene expression, which can modulate biofilm formation, genetic competence, symbiosis, motility, and the production of virulence factors76.
After reaching a certain concentration threshold, the molecules become detectable to bacteria populations, which then activate corresponding response genes that regulate various behaviours, such as virulence, horizontal gene transfer, biofilm formation, and competence (the ability to take up DNA).
AtlA is a surface-associated protein that plays a critical role in surface biogenesis, biofilm formation, genetic competence and autolysis [ 28].
The appeal to a problem of formation of research competence at pupils of comprehensive school is connected with the changing requirements of modern education to the organization and design of educational process, as well as formation of key competences at comprehensive school graduates.
The results of experimental studies and data on the characteristics and level of students' cognitive development, courage in the formation of intellectual competence in scientific research and engineering business are discussed.
The transfer of the senior stage of comprehensive school to the profile training significantly expands opportunities for the research activity of pupils that is one of productive ways of their research competence formation.
Such functions include biofilm formation, antibiotic production, competence development, extracellular enzyme production, motility, and sporulation.
