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Volume of conformational space at the level of secondary structure formation and assembly.
Key elements of β-structure folding include hydrophobic core collapse, turn formation, and assembly of backbone hydrogen bonds.
We describe the formation and assembly of photopolymerizable biomimetic hydrogel scaffolds made from protein polymer conjugates of poly ethylene glycol) (PEG) and collagen, fibrin or albumin.
Theoretical analysis of folding (the "U-to-N" transition), performed at the level of formation and assembly of protein secondary structures, outlines the upper limit of protein folding times (i.e., of the time of search for the most stable fold).
Thus, these de novo designed β-sandwich proteins should provide useful models for studying the mechanism of amyloid protofilament formation and assembly into amyloid fibrils and for designing potential inhibitors of amyloidogenesis.
This suggests important roles for meprins in tissue formation and assembly in early embryonic development.
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It is likely that cleavage of the p12-CA junction is required for both hairpin formation and capsid assembly, as appears to be the case for HIV-1 capsid assembly [15], [16].
In this regard, VAS represents an excellent system to elucidate macromolecular assembly, because many, if not all macromolecular components for the VAS formation and ultimate assembly into virions within VAS are of viral origin and thus exogenous to host cells for clear identification.
Circular dichroism (CD) spectra of the surfactant solution with various compositions illustrated the formation and supramolecular assembly of protein-like molecular architecture leading to formation of twisted nanoparticles.
The design of such nanoscale architectures and platforms requires understanding the molecular mechanisms underlying adhesion formation and the assembly of the actin cytoskeleton.
Three global regulator (IscS, TusA and NarJ) and four chaperone proteins (DsbA, DsbB, NifS and XdhC) were overexpressed to aid the formation and ordered assembly of three redox center cofactors of Rhodobacter capsulatus XDH in E. coli.
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CEO of Professional Science Editing for Scientists @ prosciediting.com