The proposed method also permits an examination of whether at all, to what degree, or within what range the available time series data can be validly represented in a particular functional format of a flux within a pathway system.
Finally, if one has valid reason to assume a particular format for a flux, such as a Michaelis-Menten or Hill function, the shift may be obtained through optimization.
The method permits the examination of a full spectrum of functional forms, as well as a determination of whether at all, to what degree, or within what range, the available time series data can be validly represented in a particular functional flux format within a pathway model.
Finally, since the range of coverage depends on the available datasets, we can, arguably for the first time, estimate how many data points are necessary to identify the functional format of a flux or what values of metabolite concentrations are needed to cover the concentration range of interest.
Just like DFE, the proposed method starts with an optional data preprocessing step, but without any assumption regarding the functional formats of the fluxes in the system.
Whereas the basic form of, say, a Leninist party, a guerrilla army or even a ghetto riot has not changed in a century, once you use social networks the organisational format of revolt goes into constant flux.
The cylindrical mesh method is for toroidally symmetric machines and utilizes data in a standard file format which represents the poloidal magnetic flux on an R–Z grid.
It's hard to know how to archive and analyze memes in a meaningful way in 2018, when the format itself is still so young, and in constant flux.
FlexFlux is the first flux analysis software to support this file format.
Note that the specific calculations to reach flux ratios from experimental data in different formats are not included in this software.
