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The relatively small number of RCTs, few overlapping treatment arms, and variability in end points studied make it difficult to formally compare therapies for relapsed/refractory CLL.
When raw data were obtained from twin studies, we attempted to fit variance components models to change scores in order to estimate the rMZ and rDZ simultaneously and formally compare models in which these two parameters were forced to be equal with models in which they were allowed to differ.
The frequency and specificity of T-cell responses, assessed by ELISpot and ICS assays, appeared similar at both vaccine doses, but the study was not sufficiently powered to formally compare dose groups.
All five modified GalK-carrying MVA-BACs converted into infectious virus, and again, though we did not formally compare growth rates, all were amplified to titres of 2.8×108 to 2.6×109 pfu/mL (final volume ∼0.5 mL) following sucrose cushion purification from 1500 cm2 of BHKs.
In future work, we plan to formally compare these different models.
Poisson regression was used to formally compare perennial differences in SCD incidence by month.
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These alterations had not been tested or formally compared with DeVita's original formula.
Here, we present an approach to formally comparing the connectivity of different cortical areas across different brains.
Many models have been proposed for genetic analysis of mastitis, but they have not been formally compared.
Currently, these models have not been formally compared by way of principled statistics such as the Bayes factor.
While stochastic methods predominate in scientific literature, they have never been formally compared to deterministic approaches, preferred by practitioners, for regional aquifer models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com