Then solving the regression Y = b1X1+.+bhXh yields the estimated haplotype frequencies (see Methods for precise formalization and methodology).
Some developments concern the quantitative formalization of the methodology and its application outside France in order to test the transferability of results and increase the number of available scenarios (Vitetta and Marcianò [53]).
The methodology described supports knowledge formalization and capitalization of experienced NDT practitioners.
The presentation of knowledge is stated to be the methodology for modeling and formalization of conceptual knowledge in the field of engineering.
Subsequently, graphical models are presented in the proposed methodology in accordance with formalization of restrictions, annotations and stereotypes through MARTE/VSL.
Just as programming systems, expert systems and knowledge bases have created corresponding software engineering disciplines, large-scale formalization projects require a carefully thought through and tested methodology.
Such so-called semi-flexible systems require careful planning, but no formalization of the corresponding decisions problems, nor any comprehensive methodology has been proposed yet.
In this regard, the employed methodology involved first the systematic analysis and formalization of the knowledge sources elaborated in the scope of this work, through which an application-specific knowledge model has been defined.
Formalization of Design Patterns refers to the techniques and methodologies that were developed for the representation of Design Patterns.
Third, we provide a detailed description of the main components and steps of this methodology: data preparation, expert knowledge transfer (including the formalization of this knowledge), and generalization of classical methods to involve prior expert knowledge.
