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Recent formaldehyde meta-analyses do not support an association between formaldehyde exposure and leukemia…………591 4.4.
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Overall, results from the meta-analyses of formaldehyde and leukemia are consistent with a lack of association and the results of our weight-of-evidence evaluation.
This result was not in accordance with the recent reevaluation from the IARC in 2009 5 and two previous meta-analyses, 2, 31 all of which suggest that formaldehyde has a causal role for cancer of the nasopharynx among workers exposed to substantial levels of formaldehyde.
Several conflicting meta-analyses attest to the uncertainty of the formaldehyde-leukemia association.
A number of recent meta-analyses have been conducted on the body of epidemiology studies concerning formaldehyde and leukemia (Bachand et al., 2009; Zhang et al., 2009; Bosetti et al., 2008; Collins and Lineker, 2004; Schwilk et al., 2010).
Search terms included "leukemia," "lymphoma," "Hodgkin," "non-Hodgkin," "hematologic neoplasm," "myeloma," "hematopoietic," "lymphatic," "formaldehyde," "epidemiol*," "occupation*," "cohort*," and "worker*." We also relied on the reference lists of several review articles and meta-analyses (e.g., Bachand et al., 2010; Zhang et al., 2010a; Bosetti et al., 2008; Collins and Lineker, 2004).
"His meta-analyses are tops.
Measuring inconsistency in meta-analyses.
Four14,20,30,32 SRs conducted meta-analyses.
Chapter 9: Analysing data and undertaking meta-analyses.
Fifteen years ago, he began conducting meta-analyses of antidepressant drug trials.
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