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This suggests that formaldehyde does not merely activate TRPA1.
Formaldehyde does not appear to increase risk in any way whatsoever.
These data strongly suggest that, at concentrations to which humans might be exposed, formaldehyde does not move beyond the nasal mucosa to cause effects at distant sites.
However, TLS by means of glutaraldehyde or formaldehyde does not maintain the bioactivity of treated tissues and it is associated with cytotoxicity induction as previously reported.
As shown in Table 14, the results from the inhalation studies generally show that formaldehyde does not induce changes in standard hematology parameters in peripheral blood.
As discussed in this review, "The panel concluded that for most persons, eye irritation clearly due to formaldehyde does not occur until at least 1.0 ppm.
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These levels of formaldehyde do not appear to impact asthmatics even though these individuals are thought to be more sensitive to irritants.
The same low concentration of formaldehyde did not induce polymerization of BSA though theoretically it will cause any protein to polymerize if the concentration is high enough.
The results indicated that formaldehyde did not induce aneuploidy under these conditions.
In this study, exposure to 500 μg/m formaldehyde did not enhance the asthmatic response to allergen.
Most of the early studies that investigated the irritant properties of formaldehyde did not properly account for the characteristic acrid or pungent odor.
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