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Categorization into high or low grade was based on the formal pathology report, with WHO grades III and IV being termed "high grade" and grades I and II termed "low grade".
Tumour tissue from paraffin blocks is collected centrally for formal pathology review and assembly of tissue micro arrays.
Overall, surveillance intervals based on endoscopic diagnosis were the same as those based on formal pathology in 92.6% of patients (95% CI 87.9%too 96.3%).
Without a formal pathology review, it is not possible to determine whether the ER-positive and PR-positive breast-ACC cases we observed are misclassified by histology and/or receptor status or represent a true variant of breast-ACC.
For "pivotal general toxicology studies" the Society of Toxicologic Pathology (STP) recommended that a second pathologist independently review the slides to arrive at more solid decisions (STP 1991), and in some cases a formal pathology working group can be convened (Ward et al. 1995).
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At the time of this study there where no formal requirements for pathology reporting of duodenal specimens, therefore, pathology reports that did not specify a Marsh stage were considered positive for CD when the pathologist commented that the biopsies were consistent with, or diagnostic of CD.
Three had specific formal training in GU pathology, three others consider GU pathology an area of interest or strength, and two had specific training in dermatopathology.
A significant difference in detection of abnormalities in 100 brains was documented, depending on whether the doctor had had formal postgraduate training in pathology.
For the questions in the formal examination on tumour pathology the score amounted to 0.47 points higher (p = 0.007), whereas it was 0.17 points higher for the questions on topics related to the previous 3 weeks.
Admittedly, this does not exclude the formal possibility that such pathologies may occur at later stages after transplantation and this will be subject of future studies.
In clinical practice 'woman centred care' and 'informed choice' have manifested in such practices as the distribution of evidenced based information brochures, client-held medical records, birth plans and formal screening for psychosocial pathology- in particular perinatal depression and domestic violence [ 15- 19].
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