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Each serine residue can potentially act as the attachment site for O-linked oligosaccharides that form the linkage region for KS.
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The funds for more basic research was found to have little effect on the formation of networks within projects but do form the linkages outside the projects.
Specific amino acids form the linkages between individual ubiquitins to form a polyubiquitin, and the nature of these linkages influences the effect that a polyubiquitin has on the tagged protein.
The deprotonated central oxygen of the enediolate ligand forms the linkage between the layers.
NMR analysis revealed that the side chain carboxylate of Pup's carboxy-terminal glutamate forms the linkage to the substrate-lysine [ 37].
It was agreed at the start of the project that sequence data would only be made available to third-party researchers outside the project in a linked anonymized (coded or pseudonymized) form, and that samples would be provided to UK10K by collaborators (sample custodians) in a linked anonymized form with the linkage key retained by the sample custodian.
For example, in the social sciences and in many other fields, journals are no longer solely in paper form and the linkage of different journals and datasets is increasing.
The key challenge in a synthesis of amine 11 is to form the glycosidic linkage with high α-selectivity.
It is noteworthy that the covalent linkage of the FAD cofactor is to H91 and hence the inactivity of the altered enzyme is probably not due to the inability to form the covalent linkage with the FAD cofactor.
These changes are likely to be essential features of the CDPSs required to form the amide linkage from AAtRNAs, as opposed to the adenylation followed by ester formation seen in ancestral AAtRS.
Both have relatively simple and very similar molecular structures; each is composed of nine amino acids arranged as a ring, which is formed by the linkage of two molecules of the amino acid cysteine (a disulfide linkage −S−S−), and a short side chain (Table 2).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com