Suggestions(2)
Exact(17)
Importantly, all TRAIL-sensitive breast tumour cell lines responded only to a TRAIL-R1-specific form of TRAIL.
Indeed, Killer-TRAIL, a commercially available active form of TRAIL exerted only a weak IL-8-inducing effect in HeLa-CD40 cells, although it triggered apoptosis with high efficiency under CHX-sensitized conditions.
The fury of Labour MPs at the legal form of trail hunting that still continues shows that what they were really after 10 years ago was a ban on posh people in riding breeches.
Thousands from all walks of life will take part in a form of trail hunting in which the pre-laid scent of a fox is followed by the hounds.
Of particular concern, the loss of soil through erosion is generally considered a significant and irreversible form of trail impact.
The increased membrane-bound form of TRAIL in macrophages may team together with either membrane-bound or soluble form of TRAIL in monocytes and CD4+ T cells, possibly causing apoptosis of bystander CD4+ T cells.
Similar(41)
Biologically active forms of TRAIL include membrane-bound TRAIL and soluble TRAIL [4], [28], [73].
This is of great importance, as it became evident that the formation of high order complexes and aggregates of recombinant forms of TRAIL (e.g., His-TRAIL, crosslinked FLAG TRAIL) increases the toxicity of the ligand to normal cells (reviewed by Koschny et al).
Often, these lures feature a large single hook which is covered by some form of trailing material as well as a metal blade which spins in the water as the lure is being retrieved.
In this study, we designed a pro-form of TRAIL (sTRAIL IL-18) in that sTRAIL IL-18L (sTRAin) is fused thatL-18, and a matrix metalloproteinasolublePs) cleavage siTRAIL introduced at the connecting sTRAIL
Similarly, for TRAIL, off-target toxicity of uncontrolled oligomeric forms of TRAIL has been reported.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com