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From 1974-1990, 23 women with stage I and five with stage II epithelial ovarian carcinoma received intraperitoneal chromic phosphate (32P) as the only form of adjuvant therapy after complete debulking and comprehensive surgical staging laparotomy.
The vast majority received some form of adjuvant endocrine treatment.
Neither form of adjuvant therapy provides any survival advantage.
No patient had previously received any form of adjuvant endocrinological or cytotoxic therapy.
Fifty-two percent of cases had received no form of adjuvant treatment.
This may be due to almost all patients receiving some form of adjuvant therapy.
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None of these patients received other forms of adjuvant systemic treatment.
Overall, approximately 30%, 48%and17%7% of women received one, two or all of these forms of adjuvant therapy, respectively.
Orchidectomy and surveillance is a safe alternative to other forms of adjuvant treatment and is not associated with an increased risk of relapse.
Two hundred and thirty five patients with osteosarcoma, aged less than 40 years, and treated by amputation or radiotherapy, were entered in a randomised trial of two forms of adjuvant chemotherapy.
Non-urban compared to urban women with breast cancer were more likely to have multiple forms of adjuvant therapy and less likely to report multiple complications.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com