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A recent crystal structure of the HSV-1 gB [25] allows computer-based homology modelling of other herpesvirus gBs, since their basic form is conserved.
This ancestral form is conserved in Pseudomonas.
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Around the OL, the IR sequence of 10 12 bp, that could form a stem-loop configuration is conserved among vertebrate species and is also proposed to be required for the initiation of replication [54].
For example, all of the phosphorylation sites in the four human BUB1B phosphorylated forms are conserved in mouse and rat and several of the sites have been experimentally shown to be phosphorylated in mouse (43).
The ability to form neocentromeres is conserved through evolution, from fungi to humans, and contributes to karyotype evolution and speciation both in vertebrates and plants.
It might be interesting to determine to what extent this form of regulation is conserved in higher eukaryotes.
The results suggest that this form of cell division is conserved across all bacteria.
Second, the propensity of precursor sequences to form hairpinned secondary structures is conserved, although the actual structures may vary.
In a previous work including PIN data [ 39], we showed that the functional form of degree distribution is conserved under sampling up to quite a low sampling fraction.
Neither the size, sequence, nor stem loop structure formed by these repeats is conserved.
In our case, predictions will be filtered by taking binding sites forming a module that is conserved in evolutionary time.
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