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Ma, M. et al. Wnt signaling in form deprivation myopia of the mice retina.
Cui, D. et al. Adenosine receptor protein changes in guinea pigs with form deprivation myopia.
We have found hypermethylation of Regulator of G-protein signaling 2 (RGS2), which was earlier reported to be upregulated in the sclera of form deprivation myopia (FDM).
Dong F, Zhi Z, Pan M, et al. Inhibition of experimental myopia by a dopamine agonist: different effectiveness between form deprivation and hyperopic defocus in guinea pigs.
Zou, L. et al. Upregulation of regulator of G-protein signaling 2 in the sclera of a form deprivation myopic animal model.
AdoRs showed to play role in growth regulation of eye and the variation in expression pattern of AdoR observed during form deprivation myopia confirms the pharmaceutical intervention may help in reducing myopia progression72.
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Yan T, Xiong W, Huang F, et al. Daily injection but not continuous infusion of apomorphine inhibits form-deprivation myopia in mice.
Proposed candidates include dopamine, levodopa, or a dopamine-like agonist that inhibited the axial elongation of occluded eyes with form-deprivation myopia in rabbits, guinea pigs or mice [43,44,45].
Title Large-Scale microRNA Expression Profiling Identifies Putative Retinal miRNA-mRNA Signaling Pathways Underlying Form-Deprivation Myopia in Mice.
"Large-Scale microRNA Expression Profiling Identifies Putative Retinal miRNA-mRNA Signaling Pathways Underlying Form-Deprivation Myopia in Mice". Plos One 11, no. 9 (2016).
We also identified their putative mRNA targets among mRNAs found to be differentially expressed in myopic retina and potential signaling pathways involved in the development of form-deprivation myopia using miRNA-mRNA interaction network analysis.
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