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The foremost limitations of the present study arise from methodological uncertainty in replicating a study based on a proprietary methodology.
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The foremost limitation of this approach is the lack of recognition of the impact of cultural viewpoints on research outcomes.
The foremost limitation of this study is the reliability of coding by hospitals.
The foremost limitation of this study is the small sample size.
Indeed, inefficient delivery of SMOs remains the foremost limitation to their usefulness as pharmaceuticals.
One of the foremost limitations in this work is the study design.
Beside the limitation of being a small-scale study, the foremost limitation is the lack of a pre-test likelihood analysis of the risk of CAD or an abnormal MPI in the study population.
First and foremost were the limitations of island health care systems, which focus mainly on primary health care, to cope with so many cases of severe illness (44 ).
First and foremost, they only allow changing yeasts within the limitations of what is achievable through natural diversity, mutation, and crossing.
The limitations of our study that could have influenced its results are first and foremost its cross-sectional design, which prevents extracting causal relationships among the variables analyzed.
We acknowledge the following limitations of the present study, which may also be viewed as recommendations for future studies: of foremost significance is the high drop-out rate in our population.
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