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The foremost difficulty of this treatment modality is related to the tooth extraction that may be associated with severe complications, such as failure to extract the whole tooth in one full piece and occasional root resorption following the treatment.
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Foremost is the difficulty of implementing absolute quantification, due to the necessity of constructing target-specific standard curves [4].
Foremost among these difficulties is the presence of homeologous gene copies (homeologs) inherited from the diploid ancestors.
Physics reformers emphasize that coming up with multiple-choice assessment tests like the FCI requires a basic research program that must focus first and foremost on identifying student difficulties with a subject.
Results from this study indicate that the two investigated BLM softwares have difficulties calculating Cu toxicity, foremost concerning the algae.
"It's often extremely easy to forget that people with mental health difficulties are people first and foremost – not objects or problems".
The foremost concerns in applying topology optimization to bone remodeling include the difficulty of handling large-scale problems and associated huge computational cost.
First and foremost, you develop a pressure response system and an ability to persevere through difficulty.
First and foremost: Really?
Children first and foremost.
Immigration is foremost.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com