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Although forced expression of EGR1 did not prevent osteosarcoma growth, forced expression of EGR1 prevented osteosarcoma cell invasion in vitro.
Forced expression of activated K-Ras (G12V) induced hepatocyte senescence as expected.
Forced expression of EGR-1 induces Bax expression and apoptosis in pancreatic cancer cells.
Forced expression of Sox9 in MSCs promotes BMP2-induced chondrogenesis and suppresses BMP2-induced endochondral ossification.
Conversely, forced expression of HMGA1 blocks differentiation of hESCs.
Forced expression of EGFR reactivates TWIST expression in EGFR-null cells.
Forced expression of LKLF was associated with markedly decreased c-Myc expression.
Forced expression of p53 increased the mRNA levels of TGFβ1/2 (Fujiwara et al., 1994; Kannan et al., 2000).
Conversely, forced expression of ZAS3 promotes osteoclastic differentiation.
Vice versa forced expression of PKD2 increases myoblast differentiation.
Forced expression of HDAC7 induces the apoptosis of the cells.
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