Sentence examples for forced discontinuation from inspiring English sources

The study was called a failure after serious side effects forced discontinuation of sirolimus therapy [25].

Interestingly, the negative consequences of forced discontinuation of MMT have recently been hypothesized following the Russian occupation of Crimea and a resulting reversal in government policy previously supportive of MMT [ 33].

However, despite the glaucoma medications, recurrent IOP elevation with intolerable ocular pain occurred in the left eye about two hours after HD initiation forcing discontinuation and was not relieved by intravenous mannitolization.

Although Methotrexate is often the most effective agent for treating severe rheumatoid arthritis, hepatotoxicity is a frequent complication of long-term methotrexate therapy, and can force discontinuation of this drug [ 51].

These side effects are seen as the limiting factor in increasing both chemotherapy and radiotherapy dosage and can force discontinuation of treatment (Keefe et al, 2000; Packey and Ciorba, 2010).

In this respect, there are reports of liver damage due to natural and drug treatments forcing discontinuation of treatment and the urgency of re-evaluating the pharmacokinetics and pharmacodynamics of these compounds [ 35- 37].

A hemorrhagic gastritis on the grounds of angiodysplasia was diagnosed at gastroscopy which forced the discontinuation of therapy.

These events may have a negative effect on a patient's vitality, social interaction, and ability to perform work and other activities, and may force a discontinuation of therapy [ 7, 8].

By performing a sub-analysis of the psychiatric adverse events forcing treatment discontinuation we observed that only rimonabant at dosage of 20 mg was associated with an increased risk of psychiatric disorders (RR 2.35; 95%CI 1.66-3.34), a difference which remains after pooling both dosages (RR 1.79; 95%CI 1.24-2.58).

According to the Journal's sources, ATL's move to ramp up production led to unspecific "manufacturing issues" within its output, which forced the full discontinuation.

The pain recurred after therapy discontinuation, so she was forced to continue lamotrigine.