Sentence examples for force for tumor from inspiring English sources

Increased chromosomal instability is the major driving force for tumor development and progression.

Tag provides the driving force for tumor initiation by blocking the activities of Rb and p53 tumor suppressors [27].

The inappropriate re-activation of embryonic signaling pathways in adult cells such as Wnt [11], Hedgehog [12] and Notch [13], can provide a driving force for tumor growth.

A recent study identified signaling within the perivascular niche as a driving force for tumor cells to acquire stem cell characteristics.

Genomic instability is a major driving force for tumor progression.

Hypoxia is the prime driving force for tumor angiogenesis, and HIFs play a key role in this process.

In our experimental model of CaP growth in the bone, administration of the anti-huRANKL MAb did not significantly inhibit osteolysis associated with the growth of C4-2 cells in the bone, suggesting that the RANKL expressed by these tumor cells is not the driving force for tumor-associated osteolysis in this model.

In addition, chemoattractant GPCRs and ligands also orchestrate the interaction of metastatic tumor cells with stromal cells, such as TAMs, ECs, and fibroblasts, which act either as "driving forces" for tumor cell dissemination or as "conditioners" of the "soil" that facilitates the settlement of metastatic tumor cells to develop secondary foci.

The pathophysiological 'EPR' effect is considered as the driving force for their tumor tropic distribution patterns.

It has been known that glucose is a primary driving force for the growth of tumor cells for more than two decades [ 29].

Given the sensitivity to mechanical restriction displayed by the EphA2/ephrin-A1 signaling complexes, one could imagine that force measurements in general could be valuable markers for tumor characterization.