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Ligands, indeed, have to withstand the pulling force elicited by cell receptors through focal adhesions (FAs).
Understandably, this staging tour de force elicited a round of delighted applause from many in the audience, completely undermining the intended horror.
In 58 other strips (10 swine), maximal active force elicited with acetylcholine (ACh) in 2ws was significantly greater than for 10ws (P less than 0.001).
At shorter ISIs both models predict the force induced by the first step; however, the force elicited by the second step is grossly overestimated by the AQLV model.
They suggested that the force elicited by elongation steps could be used to find a first order approximation of the system under study.
Rather than just showing the time course of the force elicited by our experimental paradigm, which by itself cannot be easily put in context, we present here the data we collected from monkey extraocular muscles together with the output of model simulations.
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The weight force eliciting leg withdrawal reflects the respective mechanical threshold.
The smallest force eliciting a response was recorded as the paw withdrawal threshold (20, 21).
Hence, the interfragmentary forces elicited by the nitinol staples could play a role in enhancing bending resistance through load-sharing where part of the load is redirected across the compressed osteotomy line (Bucholz 2010).
We describe here the static length-tension relationship and the transient forces elicited by small step-like elongations.
To fill this experimental gap, in the first paper in this series [3] we quantified the dynamic forces elicited by small step-wise elongations applied to passive extraocular muscles in monkeys (measured in vivo).
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