Exact(1)
This will force alterations in the receptor which might change the geometry of the interaction.
Similar(59)
The concerts are a blend of the offbeat and the very familiar, particularly since the illness of Nelson Freire, originally scheduled as a second soloist, forced alterations in Sunday's program, which was conceived as an all-French concert.
FRAP studies offer new insight into basic biological mechanisms [19], as they permit the measurement of force-dependent alterations in molecular binding and unbinding of individual proteins in situ in the physical context of the living cytoplasm [20].
Chondrocytes do not contain abundant mitochondria, but they maintain active membrane transport systems for exchange of cations, including Na+, K+, Ca2+, and H+, whose intracellular concentrations fluctuate with charge, biomechanical forces, and alterations in the composition of the cartilage matrix [ 20].
An increase in the severity of the skeletal muscle disease observed with the depletion of both Mbnl1 and Mbnl3 manifests as a synergistic enhancement of myotonia, reductions in force production and alterations in histopathology observed as an increase in atrophic fibers with a potential for increased fibrosis and central nuclei.
These downstream changes may contribute to the complex abnormalities in contractile performance found in CLC-1 deficient muscle, in particular changes that occur during the contractile phase of the contraction-relaxation cycle, such as impaired force production and alterations in rate of fatigue during isometric contractions [ 19].
Thus, it is likely that force may cause alterations in the Spectrin cytoskeleton that modulate Hippo signalling, possibly by spatially separating the N-terminal nodes of the network that bind to FERM-domain proteins, thereby inducing de-clustering of upstream pathway components and signal inhibition (Fig 4G).
The ban on hormone-altering alterations in baby bottles.
Actin polymerization can generate forces that underlie alterations in cellular morphology, protrusion, migration and chemotaxis that occur during morphogenesis.
To test this hypothesis we forced TJ alteration in confluent MCF7 cells transiently transfected with human Flag-TRAF4 grown in the presence of EGTA, a Ca2+ chelating agent that disrupts TJs [17].
Changes in the perception of touch have been linked to changes of receptive fields and response profiles of primary sensory cortex (S1) neurons37 – so-called cortical reorganisation37, 38 – raising the possibility that alterations in forcorticalption might also reorganisation37al changes related to the back.
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