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Finally our sample size is relatively small although larger than other cohorts for which responsiveness of some clinical measures has been published.
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Which responsiveness domains are most important to people?
Thus, it is important to use an animal for which longitudinal responsiveness can be investigated, as this would occur clinically in the investigation of human subjects with asthma.
In ventilated ICU patients, the grey zone approach identifies a wide range of PPV values, between 4 and 17%, for which fluid responsiveness cannot be accurately predicted, corresponding to 62% of patients in whom criteria for measuring PPV are valid.
Using this method in the anaesthetic setting, Cannesson et al. [ 18] demonstrated that the grey zone approach identifies a range of PPV values between 9% and 13% for which fluid responsiveness could not be reliably predicted.
The exceptions to this rule are IGF/INS ligands, for which receptor levels and ligand responsiveness do not correlate.
The aim with estimating individual responsiveness is to set a target for treatment effect – it may be growth response for which we now have prediction models.
The second step was aimed at determining the values for which no conclusive information could be provided concerning fluid responsiveness.
There is little evidence for which cold delivery method is most accurate in determining pulp responsiveness.
The present results provide substantial support for the reliability, validity, and responsiveness of the PSO-LIFE questionnaire in the population for which it was designed.
We believe that the present results provide substantial support for the reliability, validity, and responsiveness of the PSO-LIFE questionnaire in the population for which it was designed.
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