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This conventional definition may then not be appropriate for MTAs with prolonged administration, for which late and multiple moderate toxicities also deserve attention.
Traditional dose-limiting toxicity (DLT) definition, which uses grade (G) 3 4 toxicity data from cycle 1 (C1) only, may not be appropriate for molecularly targeted agents (MTAs) of prolonged administration, for which late or lower grade toxicities also deserve attention.
Before the war Eszterhas senior, a son of the working class, had become a successful novelist and polemicist and had risen to be an adviser to the Hungarian prime minister; he was also, as his son would find out to his horror, the author of a virulently anti-semitic tract for which late in life he was hauled before the American courts.
might have induced a polarization for which late NP600 and, possibly, NP400 might represent the overshooting high-pass filtered P3b due to high impedance for slow oscillations.
In fact, antibody to toxins may not be effective therapeutically once the toxin has bound to its receptor, as is the case for botulism, a condition for which late antibody therapy is relatively ineffective.
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This article reviews the most recent long-term clinical data for biological agents that have been approved or for which late-stage development data have been released for the treatment of patients with moderate to severe plaque psoriasis.
Or Psycho, for that matter, which, late in the game, Split resembles when the screenplay decides to make some riskier moves.
His latest comedy special for Home Box Office, which late-night viewers can catch at 2 A.M. tomorrow, opens with one of those elaborate production routines that have become the latest wrinkle in pay-cable's packaging of stand-up comics.
Nine years ago, Bennett Miller directed Philip Seymour Hoffman in Capote, for which the late star went on to win a best actor Oscar.
The idea is to remain always loyal to the esteemed mission for which the late James Cameron and his colleagues of various languages, races and nations worked.
Although this painting is still clearly figurative, Monet is taking a decisive step towards the abstract treatment of space, and the pure evocation of atmosphere and colour, for which his late canvases strive.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com