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Furthermore, we will attempt to develop novel inexpensive diagnostic tools, both for human diagnostics as well as for vector monitoring that will enhance an integrated surveillance system.
We propose to develop novel tools for vector monitoring, including the use of attractants to increase trap efficacy in the field.
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Research gaps identified in these three research areas are summarized in Box 2. Develop a comprehensive early warning surveillance system that has predictive capability for epidemic dengue using novel tools for laboratory diagnosis and vector monitoring.
The consortium comprises 12 work packages to address a set of research questions in three areas: Research area 1: Develop a comprehensive early warning and surveillance system that has predictive capability for epidemic dengue and benefits from novel tools for laboratory diagnosis and vector monitoring.
Vector monitoring system is affiliated to the health system, and performs a monthly investigation for mosquito density.
However, given the potential for man-mediated introduction of vectors highlighted by this and other studies, particular care should be taken in implementing effective vector monitoring schemes in strategic points such as airports and harbors.
The present study indicated, for the first time, the possibility to use such biomarker for monitoring vector control program in the case of human exposure to Ae. albopictus.
An important point to consider here is that we might be witness of a potential shift in vector importance, which again stresses the need for continuous monitoring of vector transmission dynamics and detailed studies of vector bionomics in the region.
Such a tool would only have value for monitoring vector control measures that reduce sand fly contact rates for humans if antibody titers are transient and increase relatively quickly after re-exposure.
We addressed the potentiality to use the Ab response against Ae. albopictus salivary proteins for monitoring vector control strategies against Ae. albopictus.
These results are consistent with previous studies which have shown that the human-specific IgG response can represent a genuine biomarker for monitoring vector control program.
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