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Taken together, these data demonstrate EPCs may play an important role in the therapeutic implications for vascular dysfunction in AD.
Several lines of evidence for vascular dysfunction were reported in migraineurs.
Several lines of evidence for vascular dysfunction have been identified in migraineurs and there is increasing evidence to suggest that in migraineurs the vascular system is impaired not only within the brain.
However, relevance of ESL disruption as causal mechanism for vascular dysfunction remains to be demonstrated.
Chronic inflammation is another important cause accounting for vascular dysfunction.
Apart from the specific treatment of vasodilatation with vasoconstrictors, there is no specific treatment for vascular dysfunction.
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Further, the results suggest that our microfluidic system may be useful in developing therapeutic strategies for the treatment of vascular dysfunction or tissue engineering.
We can reverse the early stages of vascular dysfunction if we can identify it early!
As part of vascular dysfunction large arteries can be affected.
By virtue of its ability to modulate ROS levels, p66Shc plays an important role in the aging and age-associated bioprocesses including, for example, vascular dysfunction [8].
Thus, we assessed whether ANP and/or BNP signalling is important for the vascular dysfunction observed during endotoxic shock by comparing the haemodynamic profile of WT and NPR-A KO mice following exposure to LPS.
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