In addition, development of normative values for the assessments will be essential for their ultimate application in clinical trials and clinical practice.
The critical analyses of conventional calculations of parameters results in improved calculation methods with mechanistic reasoning for the ultimate application of the data to sophisticated numerical models with explicit or discrete rockmass structure.
We hope to demonstrate that proteomic research can contribute to de-convoluting the complexity of schizophrenia, from symptom-based concepts to a biological understanding for the ultimate application in personalized medicine approaches.
The understanding of factors influencing the performance of catalysts in the air cathode of a rechargeable lithium-oxygen battery, including overpotentials for oxygen reduction/evolution and discharge capacity, is essential for exploration of its ultimate application.
Based on the comparison on pure micro-pencils, further approach (e.g. graphene coating) can be exploited for superior performance towards ultimate application in lithium-ion batteries.
As the ultimate application for these spheres is to be minimally invasive subcutaneous interstitial glucose sensors, they must be capable of being embedded interstitially.
For ultimate diagnostic application, overall results need to be improved.
Moreover, the enormous number of targets (many thousands) obtained suggests a vast heterogeneity among PC patients, thus requiring a large patient cohort for chip-based analyses to validate, optimize, and establish potential targets for ultimate clinical application.
In order to develop peptide-based supramolecular filaments and hydrogels with degradation kinetics controlled by the targeted proteases (e.g., MMPs) for ultimate biomedical applications, two important issues need to be addressed: First, the specificity of the chosen peptide substrates to the targeted protease must be quantified experimentally.
Hence, the ultimate applications of this study are geophysical, whether for hydrocarbon exploration, earthquake and structural engineering, or to the exploration of the solid earth.
