Sentence examples for for trough level from inspiring English sources

To address potential over-fitting of models for trough level prediction, cross-validation was performed on the model with the best fit (highest R 2 ).

VPA dose was increased to 1500 mg/day in patients 15 and 17 for trough levels consistently below 40 mcg/ml; levels of >50 mcg/ml were then measured in patient 17, but not in patient 15.

In contrast, in these same samples, an approximately 3-hr phase delay is observed for trough levels of CCA1 and LHY in the mutant relative to controls.

In further analyses in which we additionally adjusted for trough levels of tacrolimus and cyclosporine (model 4), we found no additional association of trough levels of tacrolimus with NODAT.

Owing to the reported overprediction of the TDx immunoassay, observed and simulated data were normalized for trough levels immediately before RYGB surgery, indicated by the time of 0 months.

In addition, blood samples for determination of trough levels of sunitinib and SU12662 were taken for Schedule 4/2 pre-dose on day 1 (cycles 1 3) and 24 h after the last dose (cycles 1 3 and 5), and for Schedule 2/1 were obtained before dosing on day 1 (cycles 1, 4, and 6), days 8 and 15 (cycle 1) and day 14 (cycles 4, 6, and 10).

Sirolimus was introduced on the first postoperative day, aiming for a trough level of 5 10 ng/ml during the first 4 weeks and 10 20 ng/ml thereafter.

These doses were chosen on the basis of a previous safety study in healthy human subjects and pharmacokinetic modelling of trough levels required for GM-CSF inhibition in synovial tissue.

This study aimed to identify factors to predict the tacrolimus dose required for achieving the target trough level for remission induction of UC.

Linear regression was used to develop predictive models for the vancomycin trough level.

In spite of this moderate to high correlation, AUC can vary up to twofold for the same trough level.