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Distance from a major road was included as a proxy for traffic exposure.
Consistent results were obtained with two different indices for traffic exposure.
In our study, stratified analyses on SES showed no differences in susceptibility for traffic exposure between the SES groups.
However, several epidemiology studies have shown associations between cardiovascular effects in people and exposure to black carbon as a proxy for traffic exposure (e.g., Zanobetti et al. 2010).
We created latent variables for traffic (exposure) and parasympathetic tone (outcome) and modeled the association dependencies between these two latent constructs.
The evidence of a causal association is strongest for traffic exposure and exacerbations of asthma in children (Health Effects Institute 2010).
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Our study revealed a significant 24% increase in the risk of experiencing multiple emergency department contacts for asthma for every log-unit of traffic exposure.
*Adjusted for SEIFA, ethnicity; **Significant at p ≤ 0.05 Our study revealed a statistically significant 24% increase in the risk of experiencing multiple emergency contacts for asthma for every log-unit of traffic exposure.
In this subgroup, a lower prevalence of asthmatic symptoms was observed; no statistically significant associations were observed between traffic count and respiratory symptoms, although for cough or phlegm the adjusted OR for the highest quintile of traffic exposure (more than 22,732 vehicles/day) was 1.48 (95%CI 0.80 2.73) compared to the lowest quintile (less than 5,608 vehicles/day).
Regardless, the chosen proxies do not reflect the true individual exposure because a large proportion of traffic exposure, particularly for adults, takes place during commuting and at the workplace (Ritz et al. 2007).
Therefore, one possible explanation for the larger effects of traffic exposure in children without these strong risk factors is that other risks, for example, dietary factors, indoor allergens, or other environmental exposures, produced asthma in the high-risk group, regardless of traffic-related exposures.
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