Sentence examples similar to for top down experiments from inspiring English sources

To identify the modification site(s), the precursor ion corresponding to the modified protein (m/z 1415.9 Da, 10+ charge state) was isolated for top-down experiments using μESI-FTICR-MS with ECD (Figure 1B, upper panel).

We demonstrate the use of NeuCode SILAC to enable multiplexed-quantitation for top-down experiments.

Label-free methods are the most accessible form of quantitation for top-down experiments.

We reasoned that the strategy would also be applicable to intact proteins and could enable robust, multiplexed quantitation for top-down experiments.

Although initially applied to shotgun approaches, NeuCode SILAC has the potential to address many of the difficulties that the aforementioned quantitative strategies have when used for top-down experiments.

In summary, NeuCode SILAC has solid potential as a robust method for obtaining quantitative data in top-down experiments and bypasses many of the drawbacks of current top-down quantitative strategies.

Unfortunately top-down experiments on this protein did not produce reliable sequence information.

MS/MS top-down experiments were also run in an effort to identify the observed proteins.

Bottom-up experiments typically provide more detailed information on molecular behavior, and top-down experiments still deal in more complicated molecules and environments.

Although internal ion formation can be used for diagnostic purposes in top down experiments with extensive a priori knowledge of the protein of interest, accommodating internal ions in a high throughput identification search strategy would cause a prohibitively large increase in fragment ion search space.

The high mass accuracy product ion measurements achieved in top down experiments provide an impressive level of specificity, requiring relatively few matching fragments for a positive identification.