Your English writing platform
Discover LudwigSuggestions(2)
Exact(19)
X-ray crystallography and molecular modeling studies revealed the inhibitor-enzyme interactions responsible for this selectivity.
The molecular basis for this selectivity was a different dissociation rate of the drug to a particular enzymatic form along the reaction pathway.
Two major factors were responsible for this selectivity: (1) hydrogen bonds between water and channel amino acids, and (2) steric restraints.
To explore the molecular basis for this selectivity, we synthesized and tested novel C5/C6-derivatives designed from quantum-based modeling of the interactions revealed in the co-crystal structures of PP5C in complex with cantharidin.
Yet the mechanisms responsible for this selectivity are not well understood.
Van der Waals energy calculations (Figure 3I) implicated residues that form the hydrophobic binding site (W623, Q635, V637, Y640 and Y657) as critical for this selectivity.
Similar(41)
Although positive effects were observed, the exact molecular reason for this selectivity-enhancement – suppression of spontaneous (non-enzymatic) hydrolysis and/or alteration of the catalytic properties of the enzyme[ 14] – remained unknown.
This selectivity for the blastemal mesenchyme is clearly advantageous for the interpretation of the present experiments since this compartment expresses PD identity.
The reported CO2/N2 selectivity of PDMS membranes was 11 12, but this selectivity for prepared PDMS/TFC-RO membranes was in the range of 6.7 22.5.
It is shown that this selectivity for Cu II) is related to the size of the 15-crown-5 ether cavity is very appropriate to house this ion.
This selectivity for smaller diameter NT growth is rationalized by the influence of the Al2O3 matrix on the sintering of the metals at high temperature.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com