Sentence examples for for this conformation from inspiring English sources

An intrinsic preference for this conformation is also exhibited by positively charged chiral PNA dimers carrying 3-amino-D-alanine or 4-aza-D-leucine residue units that provide for additional rigidity by side-chain hydrogen bonding to the backbone carbonyl oxygen.

In our structure, His130 exhibits this alternative conformation, and side chain of Tyr25 residing in the vicinity of the di-iron binding site has moved away to make room for this conformation (Figure 6 inset).

However, for this conformation to be adopted without moving the Asp394 side chain, the sugar ring had to tilt instead.

While the molecular explanation for this conformation change remains elusive, the fact that the helix is formed after flavin reduction is certainly suggestive of a key detail in the RebC catalytic cycle: substrate must bind before flavin reduction.

Apparently, the interactions between helix αM' and the thumb' are insufficient to stabilize a p51 C conformation similar to that observed in the heterodimer, indicating that the additional interactions with the RH domain are required for this conformation to be significantly populated.

Molecular dynamics simulations of the V266H variant showed that His moves to the C-terminal side of β-strand 8 and displaces Tyr towards helix 3. Experimental evidence for this conformation of His was observed in the E124A,V266H double mutant as well as the E124A,Y197C,V266H triple mutant.

A prominent hypothesis explaining the selectivity of Imatinib is that Abl has an intrinsic ability to adopt an inactive conformation (termed DFG-out), whereas c-Src appears to pay a high intrinsic energetic penalty for adopting this conformation, effectively excluding Imatinib from its ATP pocket.

For 1,7-C60 1,7-C60 this C2F5 2mathis variability results in six different conformationwhose energies variabilityicantly in dependence on the resultse orinntationsixf C2F5 groups.

For historical reasons, this conformation had been called 'polyproline helix', although most PPIIs comprised non-proline residues and some even contain no proline at all (8).

Yet, given the paucity of structural data for asymmetric transporters in this conformation and in a lipid membrane, this work represents an important contribution to the structural understanding of ABC transporters in general.

In trypanosome biology, there is no term for a cell with this conformation.