Sentence examples for for this checkpoint from inspiring English sources

"I was screaming at them that there was no need for this checkpoint, and no need to open fire".

And I'll never forget that at checkpoint Invalidenstraße – the British army was responsible for this checkpoint – the day after, there were some Scottish army bagpipers and the troops served tea and biscuits!" "I was living in Berlin at the time when I had a call from a friend urging me to get down to the wall as soon as possible as there was something going on.

To gain further insight into the molecular requirements for this checkpoint, we investigated other mutants known to be defective in centrosome orientation.

The exosome subunit Rrp6 is required for this checkpoint in Saccharomyces cerevisiae, but it is not known whether Rrp6 also plays a role in mRNA surveillance in higher eukaryotes.

Nonetheless, the potential modulation by CHEK2 of both BRCA1 and BRCA2 would point to an important function for this checkpoint kinase in the DNA damage repair pathways implicated in the development of breast cancer.

In this model, a strong selective pressure then exists for mutations that compromise this checkpoint, for example in the ATM-Chk2-p53 pathway, resulting in tumorigenic progression.

It has been proposed that infection (for example, with Porphyromonas gingivalis in patients with periodontitis) may be a critical trigger for progress through this checkpoint, potentially due to cross-reactivity with bacterial antigens, adjuvant effects of pathogen-associated molecular patterns, targeting of alternative antigen-presenting cells, or a combination of these [ 9].

The CD8/4 profiles of these double-deficient mice were similar to those of RAG1-deficient mice, indicating that CBAP is dispensable for thymocyte death at this checkpoint.

One of the most prominent border crossing spots for foreign visitors in pre-1989 Berlin, this checkpoint is a grim reminder of the city's progress over the past 27 years".

This checkpoint role for CCR4 and DHH1 has been subsequently confirmed by other laboratories [28] [29] [30] [31] and a role for BRCA1 in G1/S checkpoint arrest following IR damage has been previously described [32].

The high prevalence of TP53 mutations in hereditary [20] and sporadic [38] ovarian carcinomas suggests that this gene is a frequent mutational target of the selective pressure for aneuploid cells to overcome this checkpoint.