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Future studies elucidating the fundamental biology of Tregs in human tissues will be indispensable for defining their abnormalities in diseases and the potential exploitation of these cells to treat diseases.

All three XYY males would have met SLIC criteria for SLI (as specified in the Method section) if not for their chromosomal abnormalities.

First, we propose a new method to identify case reports concerning rare diseases and to subsequently annotate them for their phenotypic abnormalities in 'Methods'.

By contrast, women's satisfaction with their targeted care for their cervical abnormality was higher in the HPV triage and informed choice groups than in the cervical smear group at two weeks (HPV and smear test: t=1.96, df=129, P=0.05; HPV and informed choice: t=2.37, df=118, P=0.02).

The available data on the individual components of selected polyherbal formulations; Z. officinalis[ 8, 9], P. nigrum[ 10, 11], T. belerica[ 5, 12] and O. mascula[ 13] provide an indirect evidence for their effectiveness in cardiovascular abnormalities using non-specific experimental models.

Although a number of autoimmune diseases have been superficially examined for their potential association with abnormalities in the IGF-I/IGF-IR pathway (Smith, 2010), a substantial link between this pathway and the pathogenesis of these diseases has not been established.

Furthermore, to examine their livers for abnormalities, rodents must be sacrificed and their internal organs surgically isolated.

Another 17th-century figure provides Leroi with a model for his endeavour: Sir Francis Bacon recommended the collection or description "of all the monsters and prodigious products of nature, of every novelty, rarity or abnormality", not for their own sake, but for what they reveal about the normal laws of nature.

Intriguingly, people withthe so-called e4 variant of a gene known as APOE the largest genetic risk factor for developing Alzheimer's later in life are at a higher risk for developing abnormalities in their entorhinal cortex.

Currently, in the era of screening mammography, LCIS and ALH are not uncommonly identified as the most significant pathology in biopsies performed for breast abnormalities and their management remains controversial.

Furthermore, clinicians prescribing sibutramine should monitor their patients for electrocardiogram abnormalities and be cautious in coprescribing drugs known to prolong the QT interval (e.g., certain antipsychotics, antidepressants, and antiarrhythmic agents).

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