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If no condition records were available for the week of conception, then we used the condition records for the week prior to conception.
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We extracted the mother's condition records during the week of conception.
Women self-reported occupation twice for the periods of conception to 20 weeks of gestation and 20 weeks to birth.
The respiratory tract develops after 4 weeks of conception from the ventral wall of the foregut.
Human fetal tissue (between 10 and 15 weeks of conception) was obtained from the Birth Defects Laboratory at the University of Washington.
Failing that, over-the-counter pregnancy tests can reveal pregnancies within two weeks of conception.
Within two weeks of conception, a female embryo's primordial germ cells begin the assembly of her future children.
If information about the week before conception was also missing, then we checked for records two weeks before conception and one week after conception.
For many women, the science of conception is already a refined one.
The enrollment urine sample was set to a time of 0. For pregnancy samples, we calculated the number of weeks since conception for each urine sample by subtracting the date of conception from each urine sample collection date.
For the 5914 cases for which we know the date of the last menstrual period (DLMP), we estimate the date of conception as occurring 2 weeks after the DLMP before the focal pregnancy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com