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Thus, the assay has a great potential as a high-resolution molecular typing tool for the study of outbreaks of cod francisellosis.
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PFGE has been considered as the "gold standard" for the study of hospital outbreaks because of its high degree of isolate differentiation [ 30].
We suggest that diagnostics for SaV should be included in the study of gastroenteritis outbreaks in adults, especially when clinical signs suggest NoV as the causative agent but no diagnostic confirmation can be achieved.
In addition to those reporting guidelines listed in the questionnaire, one respondent specified the ORION statement for studies of outbreaks and nosocomial infections [ 35], and two respondents cited the International Committee of Medical Journal Editors (ICMJE) Uniform Requirements for manuscripts submitted to biomedical journals [ 36].
This need exists for epidemiological studies of outbreak strains, where strain discrimination is the primary focus, as well as for population genetic studies where genomic information is of central importance.
In a study of outbreak control for SARS, Chowell et al. suggest "… the strong sensitivity of R 0 to the transmission rate β indicates that efforts in finding intervention strategies that manage to systematically lower the contact rate of persons of all age groups promise an effective means for lowering R 0" (4 ).
During flu season, one place to check for the level of outbreaks is Google Flu Trends, which extrapolates outbreak levels from the rise in flu-related searches.
Watch for the symptoms of outbreaks and treat them promptly.
A 0- to 3-day time window of interest for skin rash was based on prior studies of outbreaks of cercarial dermatitis, which generally occurs within the first 2 days of water recreation [Centers for Disease Control and Prevention CDCC) 1992; Hoeffler 1977; Mulvihill and Burnett 1990].
In previous studies, similar tools were successfully applied for the detection of outbreak vehicles.
Population-based seroprevalence studies are needed to determine seronegativity and explore the reasons for this outbreak.
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