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This is of interest because, based on clinical data, a plasma level of 500 ng/ml of ECDHER2 was set as a cutoff value for the stratification of data analysis in a study showing that the shed ECDHER2 level in serum was significantly associated with clinical outcome.
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Lack of data analysis.
Therefore, we developed a method for stratification of data and evaluated the method using previously characterized cases.
This is not always possible by means of stratifications in graphical data analysis.
Stratification of data by sample type revealed the comparative utility of the assay for different forms of EPTB, and complements the meta-analysis by Denkinger et al. [ 44].
Owing to the stratification of the cohort, these last data have to be regarded for exploratory purpose.
In order to correct for the stratification in the genotypic data, the first (top) 100, 5, and 80 principal components were used in the EIGENSTRAT analysis of California, New Mexico, and the combined data sets, respectively.
The median of pack-years (50) was used as cut-point for the stratification analysis.
Many of the studies presented lacked a data analysis strategy to distinguish the effects of ethnicity from the influence of other important socioeconomic factors, for example, by adequately adjusted regression models or stratification schemes.
One limitation of this study is that, due to the small number of subjects, we could not perform a stratification analysis of data.
Data were weighted afterwards to correct for the disproportionate stratification of the underlying causes of death.
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