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A peptide linker between GFP and the target protein is required for the stability and function of fusion proteins.
Using a shorter length may prevent detection of any long-range interactions that might be crucial for the stability, and function of the RNA molecule.
HSP90 is a molecular chaperone required for the stability and function of a number of proteins implicated in cancer cell growth and angiogenesis, including HIF-1α [28].
This is an important feature required for the stability and function of snoRNPs [ 8].
Disulfide bonds are required for the stability and function of a large number of proteins and disulfide bond formation is essential for proper protein folding [ 40].
Conversely, heat-shock protein 90 (HSP90) is a chaperone required for the stability and function of these proteins, especially ER, HER2, AKT, and RAF [ 12].
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Hoogsteen-position pyrimidines promote the stability and function of the MALAT1 RNA triple helix.
Negatively charged residues found in NASP are important for the stability and proper functioning of the protein [ 16].
Bochman, M., Paeschke, K. & Zakian, V. DNA secondary structures: stability and function of G-quadruplex structures.
We show that this protein is a core component of the Ska complex, required for both complex stability and function.
Post-translational modifications of tubulin are crucial for regulating microtubule stability and function.
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