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These triblock and star-block copolymers could prove useful as nanocarriers for the solubilization and delivery of hydrophobic drugs.
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Thus, conjugation of PTX to heparin may be useful for the solubilization and targeted delivery of PTX to solid tumors.
Series of fluid HII and QL mesophases with complex architectures were rationally designed and prepared for the solubilization and potential delivery of food additives.
In this chapter, the application of oil-in-water nanoemulsions for solubilization and delivery of hydrophobic pesticides is reviewed.
A series of monomethoxy poly ethylene glycol -poly(lactide) (mPEglycol -polyck copolactidewere synthesized, and mPEG-PLA micelle was fabricatediblocksed as a nanocopolymersr solubilization and delivery of a promising anticancer drug ethaselen.
Although several methods including drug delivery systems were investigated [3], developing a ethaselen delivery system for higher selectivity, efficient solubilization and delivery of ethaselen to the intended site without provoking any adverse reactions is still a challenge.
From this research, we found that PEG-PBLG nanoparticles are useful for the solubilization and sustained release of HCPT.
A series of monomethoxy poly ethylene glycol)–poly(lactide) (mPEG PLA) diblock copolymers were designed according to polymer drug compatibility and synthesized, and mPEG PLA micelle was fabricated and used as a nanocarrier for solubilization and oral delivery of Cyclosporine A (CyA).
This study establishes proof-of-principle for use of acyclic CB[ n]-type containers for drug solubilization and delivery.
Lipophilic compounds represent a class of bioactive molecules that pose unique challenges for solubilization and delivery to tissues and cells in aqueous environments.
For example, host factors such as midgut pH and proteases contribute to the solubilization and activation of toxin following ingestion.
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