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For example, a metric of validation for the present implementation, which relies primarily on in vitro assay data and chemical properties for predicting toxicity, would be in the context of actual toxicity measures.
The reactions building up the network were implemented as described in Additional file 1: Table S1 of Dell'Orco et al [ 15] and in Dell'Orco and Koch [ 19], and the parameters that needed tuning for the present implementation are reported in Table 3.
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The HHT method is adopted in the present implementation for the solution of the dynamic equilibrium equations.
The present implementation of Seeder allows for motif searches in the mode 'one occurrence per sequence' (oops).
The basic idea and the present implementation appear useful indeed for field studies on animal navigation and related topics.
For the present application, the implementation is separately completed on the three profile sets of RP, NP, and TP.
For the present study, the pybel implementation was used [30].
For the present study, the SVM implementation used was provided by the e1071 [61] package from R. This library provides an interface to libsvm which allows classification or regression [62, 63].
For each strategy, we present implementation considerations and discuss a range of accompanying challenges and opportunities.
In the present study, implementation of LH for EC was evaluated in a large oncology network in the Netherlands.
We describe the general workflow for the presented method, provide its software implementation (see Additional file 1) in GRASS GIS [16] and demonstrate our method on two use cases.
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