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PW is a pathologist, the principal investigator for the PREDICT project and has made substantial contributions to the conception and design of PREDICT.
We thank Jeremy Bockholt for the bioinformatics support for the PREDICT subjects.
Nevertheless we believe that the framework developed for the PREDICT project has the potential to help scientists, clinicians and the public to overcome the translational research roadblocks.
The design team met weekly to bi-weekly as required from March to June 2006 and created an outline for the PREDICT process, making decisions about who would be approached, when and how to approach potential participants, consent, obtain a blood sample and re-contact patients after consenting.
For the PREDICT array, given the paired design, conditional logistic regression was used.
MK and IN originated the idea for the Predict study and led on its design.
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Much better agreement was observed for the predicted log Kow.
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