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18 A variety of theories for progressive beta cell failure have been proposed as explanations for the pathogenesis and progression of type 2 diabetes.
Epigenetic alterations may be very important for the pathogenesis and progression of cancer [152,153].
This outcome indicates that inducible forms of Hsp70 are not necessary for the pathogenesis and progression of neuropathy.
Oxidative stress is one major molecular mechanism responsible for the pathogenesis and progression of several NDDs [ 5].
In summary, our current results provide the primary evidence that the polymorphism rs9904341 in the promoter of survivin is a genetic susceptibility factor for the pathogenesis and progression of PCa in Chinese population.
Loss of KLF4 is critical for the pathogenesis and progression of digestive system tumours, including hepatic, gastric, colorectal and pancreatic cancer (Wei et al, 2005; Kanai et al, 2006; Wei et al, 2008; Li et al, 2011, 2012).
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Thus, genetically encoded redox sensors are useful for the study of the pathogenesis and progression of multiple diseases.
As the immune system plays a pivotal role in cancer, the study of tumor microenvironment, with regard to the immune component, may provide valuable information for a better comprehension of the pathogenesis and progression of the disease.
These findings suggest an intriguing potential immunomodulatory role for aldosterone, which could be important in the pathogenesis and progression of lupus nephritis.
The wealth of early affected loci strongly argues for a prominent role of epigenetic mechanisms in the pathogenesis and progression of MDS and AML.
It is preferential to elicit how a molecular pathway modulates the pathogenesis and progression of NASH for therapeutic use of AC extract.
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