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In the following sections we describe how appropriate settings for the parameters of the BtA-workflow can be found automatically.
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In this paper we propose how to choose all relevant parameters of the BtA-workflow automatically (see Methods section), which allows for the analysis of many networks without the need for human interaction.
For one: the parameters of the trials.
The BtA-workflow requires two additional parameters to control which nodes will constitute individual motif regions.
In the next section we suggest several improvements to the BtA-workflow (Fig. 1), which can be sketched as follows: Initially, multiple local network measures are applied to each node, which yields a multi-dimensional characterisation in form of a feature vector.
Thanks, George Osborne, for liberalising the parameters of boring.
However, a good PDF estimate is needed in the BtA workflow to determine outlier nodes.
Considering the BtA workflow as presented in this paper, the technique can be easily adapted by including different local network measures in the analysis.
With the validated method, we sought to test parameters of the workflow.
To encourage the use of the BtA methodology by other researchers, we provide our implementation of the workflow including the automatic parameter determination for download (http://www.biological-networks.org/).org/
We encourage users to use these workflows and fine-tune parameters of tools in the workflow as they see fit.
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