Sentence examples for for the optimal development and function from inspiring English sources

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Furthermore, CD8+CD28−Foxp3+ cells (CD8 Tregs) play an important role in the ameliorative effects of hCDR1 as well, and were shown to be required for the optimal development and function of CD4 Tregs [9].

However, PI3Kδ signalling is also essential for the optimal development and function of Treg [ 10, 11, 41 ].

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Docosahexaenoic acid (DHA; 22 6n − 3) is highly important during pregnancy for optimal development and functioning of fetal neural tissue.

NKp46 was critical for the subsequent development of antiviral and antibacterial T cell responses, which suggests that the regulation of NK cell function by NKp46 allows for the optimal development of adaptive immune responses.

While the importance of vitamin D levels for normal bone formation, parathyroid function and intestinal calcium absorption are well documented, the levels needed for optimal brain development and function are unknown [ 26– 29].

Farah said her results were evidence for the existence of a sensitive period, early in a person's life, that determined the optimal development of the cortex.

While the critical importance and the need for sleep in children may seem obvious, many of our children fail to get the sleep they need for optimal physical and psychological development and functioning.

The auxiliary variable stands for the optimal weighting function.

The optimal growth and development of infants and young children are fundamental for their future [ 1].

Mn is an essential trace metal necessary for normal brain development and for the optimal functioning of multiple enzymes, including Mn-superoxide dismutase and glutamine synthase (Brock and Walker 1980; Takeda and Avila 1986; Wedler and Denman 1984).

The costimulatory molecule CD28 is required for optimal activation and function of naive T cells; however, its role in Treg function has been difficult to dissect, as CD28 is required for thymic Treg development, and blockade of CD28-ligand interactions has confounding effects in trans on nonregulatory cells.

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