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Protein farnesylation is required for the localization and function of several proteins pivotal to signal transduction pathways and cytoskeletal organization, including the Ras proteins.
Protein farnesylation is required for the localization and function of several proteins pivotal to signal transduction pathways and cytoskeletal organization, among which are the ras proteins.
Interactions between Aurora-B and other CPC components are required for the localization and function of the CPC and are also necessary for the activation of Aurora-B.
We therefore considered the possibility that Ark1 is required for the localization and function of Moa1, which prevents bi-orientation of sister chromatids at meiosis-I (Yokobayashi and Watanabe, 2005).
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Therefore, for further studying the localization and function of AtKinesin-13A, Arabidopsis root tip cells were used.
Prenylation is a posttranslational modification essential for the proper localization and function of many proteins.
In summary, this study has identified critical amino acids needed for the normal subcellular localization and function of Nav1.7.
A change of conformation of this structure was expected for a switch of the PTEN localization and function into the nuclear environment (Fig. 8).
Post-translational modification of proteins by the lipid palmitate is critical for protein localization and function.
These results suggest that CENP-H may be crucial for the appropriate localization and the proper function of the kinetochore.
These studies suggest that the interaction of γ-tubulin with NEDD1 is critical for its localization and function.
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