The difference between the distributions for this Rhizophagus sp. run and for gra, the smallest of the large control genomes genome (88 Mb, supplementary table S1, Supplementary Material online) reveals an important property of our approach.
This argument is illustrated by the average expected heterozygosity of 0.245 (SE = 0.023) for the 43 trees of the large control population that were not selected to be part of the small control population, whereas that of the 28 trees making up the small control population was 0.319 (SE = 0.028).
Therefore, even if this comparison does not correct for the fact that the large control population was not randomly chosen, the genetic diversity that it contains was likely representative of the species natural populations.
SR were higher for Rhizophagus than for the larger control genomes, but lower with respect to the small genome control data sets.
Then, algorithms for the largest invariant subset and the largest control invariant subset contained in a given subset are proposed.
This has been the case in China, for example, which has tripled the area of planted forest between 1990 and 2010 to 60 Mha for the large scale control of desertification (FAO 2010).
Both case-control and case-only study designs are feasible, with the latter adding flexibility and reducing the need for a large control sample size, which can be particularly difficult to ascertain in admixed populations.
These techniques have dramatically reduced the number of required animals according to the 3R principles described by Russel and Burch 1959 [ 16]: each animal can be scanned repeatedly in a longitudinal study, avoiding the need for large control groups.
A drug--praziquantel--that has all the qualities of an ideal candidate for the large-scale control of Schistosomiasis is readily available.
Selection criteria were necessarily based on those used for the larger randomised controlled trial.
