Age, gender and enrolment status were used for the imputation model, but not imputed themselves.
This method is considered more appropriate for the imputation of categorical data because it does not assume normality of imputed variables [ 22].
Finally, we report results for the imputation of HLA classical alleles and amino acids identifying three independent effects to MHC class I molecules.
Then, the procedure uses the actual observed value for the imputation.
This experiment is conducted to compare GD with MAP as a solver for the imputation problems.
for the imputation of γ i (β,t) ((iin bar {V})).
Moreover, additional adjustments would still be needed to take proper account for the imputation of the skill measurements.
The main effect for the imputation method was significant both for subpopulation differences and for the regression coefficient β2.
To determine optimum number of nearest neighbors for the imputation step (bandwidth, McGarrigle 2013), 100 of the oldest intact plots were selected.
Solving each of these problems requires a computational effort that is at least an order of magnitude greater than the evaluation of a Gaussian likelihood, so various approaches for the imputation with CGs are discussed below.
Phased haplotypes were downloaded from the HapMap database (http://www.hapmap.org) as input for the imputation.
