This idea has immediate appeal since it provides an elegant route to the generation of new functions without compromising essential ancestral gene functions.
Duplicated genes provide raw material for the generation of new genes, which, in turn, facilitate the generation of new functions.
Gene duplication events are important for gene family evolution, because duplicated genes provide the raw materials for the generation of new genes, which in turn facilitate the generation of new functions.
Gene duplication events are important to gene family evolution because duplicated genes provide the raw materials for the generation of new genes, which in turn facilitate the generation of new functions.
Retroposition, a major mechanism of gene duplication, can provide raw materials for the generation of new gene functions [1] and is an important process shaping the evolution of genomes [2].
Gene duplication is classically discussed as leading to neofunctionalization (generation of new functions), subfunctionalization (generation of a varied function), or pseudogenization (loss of the gene and its function).
In summary, this PD-proteome provides the community with a valuable resource for cross-referencing from other PD-related experimentation or for the generation of new hypotheses about the functioning of these important cellular structures.
The aim of this article is to show users how to best exploit the knowledge on protein function and sequence variation provided by UniProtKB/Swiss-Prot for the generation of new hypotheses describing the mechanisms underlying genetic diseases.
Other than the standard route of gene duplication, which primarily creates subfunctionalized or (rarely) mildly modified new gene functions (reviewed in [39]), there is no known aggressive process for the generation of new genes.
Which of these cells are more helpful for the generation of new genes?
This allowed for the generation of new items in case of insufficient coverage.
